At the heart of the multi-modal hub, Latitude 46 is served by numerous lines:
- City public transport (TAC network) "Gare d'Annemasse" stop in front of the restaurant: Tango, 5, 8, DA lines
- SNCF train station 50m away: TER and Léman Express (Geneva airport link)
- Bus station 50m away: lines Y02, Y04, Y11, lines H and I (Proximiti)
- Freeway exit n°14 2km away